Leucovorin calcium is also used to prevent and treat the toxic effects of high-dose methotrexate when used to treat osteosarcoma and other types of cancer. It is also used to treat overdoses …

Jul 29, 2025 · FOLFIRINOX is a four-drug chemotherapy regimen that contains folinic acid (leucovorin), fluorouracil (5-FU), irinotecan, and oxaliplatin. It is primarily used to treat …

Sep 27, 2023 · Leucovorin Calcium is a form of folic acid used to reduce the side effects of large doses or accidental overdose of medications that can reduce the effects of folic acid in the body.

Feb 1, 2025 · Leucovorin is used as an antidote to the harmful effects of methotrexate (a cancer medicine) that is given in high doses. It is used also to prevent or treat certain kinds of anemia.

Oct 21, 2024 · Find patient medical information for Leucovorin (Wellcovorin) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings

Dec 12, 2022 · Leucovorin Calcium Adult Medication This information from Lexicomp ® explains what you need to know about this medication, including what it’s used for, how to take it, its …

Leucovorin comes as a tablet to take by mouth. It is usually taken every 6 hours until laboratory tests show it is no longer needed. Sometimes leucovorin is taken on a different schedule, …

Sep 28, 2025 · Leucovorin is a folic acid antagonist used in combination with other chemotherapy medications to improve the efficacy of the medication or ‘rescue” normal cells.

Mar 19, 2025 · Excessive amounts of leucovorin calcium may nullify the chemotherapeutic effect of folic acid antagonists.

The pharmacokinetics of leucovorin was evaluated after intravenous, intramuscular and oral administration of a 25 mg dose of leucovorin calcium to healthy male subjects in a randomized …