HPV cfDNA is a highly effective tumor marker for monitoring disease progression and treatment response in HPV-positive ...

Our understanding of the molecular pathogenesis of LAMA2 -related muscular dystrophy ( LAMA2 -MD) requires improving. Here, we report the phenotype, neuropathology, and transcriptomics data (scRNA-seq ...

Sex-biased gene expression in the body organs evolves rapidly, supporting a mosaic model of maleness and femaleness across tissues and thus challenging binary views of sex characteristics in mammals.

An organoid-based screening platform that allows one-gene-at-a-time knockdown across a whole tissue has been used to identify the genes that regulate closure of the neural tube in humans.

This study offers a valuable theoretical framework for quantifying molecular transport across interfaces between coexisting liquid phases, emphasizing interfacial resistance as a central factor ...

Structural reconstruction of thousands of ancient nitrogenases through Earth’s history uncovers architectural constraints that shaped their evolution under global environmental transitions.

We present an integrated approach to derive multimodal MRI markers of cognition that can be transdiagnostically linked to psychopathology. This demonstrates that the predictive ability of neural ...

Non-essential amino acids such as glutamine have been known to be required for T cell general activation through sustaining basic biosynthetic processes, including nucleotide biosynthesis, ATP ...

The analysis of neural morphology across Heliconiini butterfly species revealed brain area-specific changes associated with new foraging behaviours. While the volume of the centre for learning and ...

This study provides valuable insights into human valve development by integrating snRNA-seq and spatial transcriptomics to characterize cell populations and regulatory programs in the embryonic and ...

Fully autonomous home-cage training system HABITS enables mice to learn complex cognitive behaviors without human intervention, expanding behavioral paradigms and optimizing training efficiency ...

Uptake of cell-free chromatin particles released from dying cells and carrying non-coding DNA could redefine mammalian genomics.