Viral vectors are key delivery tools for advanced therapies, enabling gene transfer to treat inherited disorders, cancer and other serious diseases. Despite rapid clinical progress, manufacturing ...

The successful application of RNA therapies to rare diseases, neurological disorders, and other conditions as well as the plethora of biopharmaceutical companies developing new RNA-based therapeutics, ...

Double-stranded RNA (dsRNA) is a critical immunostimulatory impurity in mRNA production and poses a problem for the downstream purification methods vital to manufacturing mRNA vaccines and ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells. How genes are turned on ...

African swine fever (ASF) is a fatal viral disease of domestic and wild pigs, with mortality rates reaching up to 100%. In the absence of a safe and effective vaccine in non-endemic countries, it is ...

Ion exchange chromatography (IEX) is a versatile and widely used technique for separating biomolecules based on charge. It plays a critical role in protein purification in research and ...

To purify increasing amounts of biotherapeutics more efficiently, the use of high flow rates or greater resin bed heights during downstream chromatography steps is a tantalizing option. A limitation ...

This webcast features: Sara Sousa Rosa, PhD, Research Fellow, UCL Biochemical Engineering. mRNA vaccines have emerged as a promising technology for a number of applications, from prophylactic and ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Multicolumn Countercurrent Solvent Gradient Purification (MCSGP) process technology ...