A 19-year-old woman with a history of depression and anxiety symptoms was admitted to the hospital because of seizure, ...

This Double Take video explores the link between certain strains of human papillomavirus and cancer and reviews the evidence ...

Understanding today’s corporatization of U.S. health care requires seeing it from a historical perspective, as a process that began with a change in the business model of care delivery in the 1920s.

Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is ...

Abelacimab is a fully human monoclonal antibody that binds to the inactive form of factor XI and blocks its activation. The safety of abelacimab as compared with a direct oral anticoagulant in pati ...

Artificial intelligence could revolutionize health and health care in low- and middle-income countries by addressing the large knowledge and judgment gaps that make care delivery poor. But for AI t ...

In this issue of the Journal, Aronne et al.1 report the results of a trial comparing tirzepatide and semaglutide, two drugs currently approved to treat obesity that consistently lead to reductions ...

Homozygosity for the PNPLA3 risk allele is linked to liver fat accumulation. In phase 1 trials, JNJ-75220795, a hepatocyte-targeted GalNAc-conjugated PNPLA3 siRNA, reduced liver fat in PNPLA3 ...

Nonrandomized observational analyses have been promoted as alternatives to randomized clinical trials. However, randomization ensures balance between groups, whereas nonrandomized studies are often ...

The most important attribute of patient-centered care is the active engagement of patients when fateful health care decisions must be made — when they arrive at a crossroads of medical options ...

Maintaining medicine’s commitment to excellence while remedying our failures requires distinguishing unnecessary trainee harms from necessary discomforts. Why is it so hard to make these ...