Women face more structural and interpersonal barriers to research participation, highlighting the need for targeted equity-focused interventions.

Early-onset CRC mortality among adults aged younger than 45 years has increased over 2 decades, particularly affecting those with rectal cancer.

Bariatric surgery, including Roux-en-Y gastric bypass and sleeve gastrectomy, was associated with a moderate reduction in the risk for colon polyps and CRC.