Chromosomes carry genetic information for biological sex, which generally assigns women two X chromosomes and men XY ...

Extra X chromosomes significantly increase the risk for systemic lupus erythematosus (SLE) and Sjögren disease, with the prevalence of these conditions being higher among patients with Klinefelter and ...

X-linked agammaglobulinemia (XLA) is an immune disorder that causes extremely low levels of B cells, which are an important part of the immune system. XLA can put a person at risk of frequent ...

Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have identified a mechanism that protects the female brain from genetic diseases. Although one of the two X chromosomes is ...

X chromosome reactivation contributes to reducing the signs of disease in the female brain. Female cells have two X chromosomes and male cells have one X chromosome and one Y chromosome. So that the ...

Scientists at The Hospital for Sick Children in Canada have discovered a gene that may be responsible for defining behaviors ...

In female mammals, one of the two X chromosomes is usually inactive and forms the so-called Barr body. The image shows a cell nucleus with the Barr body marked in green. Unlike men, who carry one X ...

The cells of female mammals randomly inactivate one X chromosome to keep gene dosage the same as in males. Does it matter which X becomes inactive? Surprisingly, it does, according to new research ...