Skene’s gland cancer may be uncommon, but its potential for serious consequences makes recognition of symptoms and early detection crucial.

Microscopic studies of the Skene’s glands show “secretory” cells, i.e., cells that secrete fluid. Women produce prostate-specific antigen (PSA). PSA is a compound unique to the prostate gland.

Urethral glands can, and so can salivary glands, normal breast tissue and some cancers besides prostate. The parallel structures to the prostate gland in women, Skene’s glands, may produce PSA ...