All cells, whether big or small, short or long, rely on proteins to function properly. In most cells, transporting these proteins is relatively simple. Neurons in the brain, however, face a ...

In certain contexts, the Notch receptor may participate in “reverse signaling,” influencing neighboring cells directly.

T cell receptors (TCRs) are fundamental to the adaptive immune system, playing a pivotal role in recognising and responding to pathogenic challenges. Generated through the process of V(D)J ...

A new study reveals the hidden mechanism a common gut bacterium uses to damage the colon, solving a mystery that has puzzled ...

Iron is indispensable for oxygen transport, DNA synthesis and energy production, yet free iron is potentially toxic. Cellular uptake of iron is primarily mediated by the transferrin receptor (TfR), ...

"I think PAGER has potential for impact, both in the G protein coupled receptor biology field, and in synthetic circuits or cell-based therapies," said Alice Ting, professor of genetics at the School ...

Edited by Karen Young Kreeger J.A. Bennett, R. Dingledine, "Topology profile for a glutamate receptor: Three transmembrane domains and a channel-lining reentrant membrane loop," Neuron, 14:373-84, ...

Researchers say findings may have relevance to understanding cell biological pathways that contribute to nerve repair after injury or neurodegeneration.

Have you ever wondered why freshly brewed coffee smells so delicious, but tastes bitter? New research from the University of ...

Mosquitoes are the most dangerous animals in the world. The diseases they transmit have spread death and misery since time immemorial. Aedes aegypti is a particularly treacherous mosquito because it ...