It wouldn't be a normal victory Monday for the San Francisco 49ers without Kyle Shanahan providing discouraging injury news.

The Arizona Cardinals are back in action in Week 11, facing the San Francisco 49ers for the second time this season. The 6-4 ...

The Arizona Cardinals and San Francisco 49ers revealed their final inactives report for Week 11 - who's in, who's out?

Signs pointed toward CB Deommodore Lenoir not being able to play for the San Francisco 49ers on Sunday, but their inactives ...

The 49ers keep repeating the same sequence when it comes to their top wideouts -- banner year, difficult contract, bad blood ...

San Francisco 49ers receiver Brandon Aiyuk has had the guaranteed money in his contract for next season voided.

The San Francisco 49ers are finally getting healthy, as Brock Purdy returned to action to throw 200 yards and three ...

Just one year after a massive contract extension, the 49ers and Brandon Aiyuk's relationship may be coming to an end.

Among the decisions the San Francisco 49ers will have to make throughout the offseason, it sounds like trading Mac Jones is a ...

After a seemingly endless news cycle over the last two years, the San Francisco 49ers appear to be reaching the end of the ...

San Francisco 49ers general manager John Lynch shares his honest perspective on Brock Purdy’s return as the team's starting ...

The franchise is preparing to part ways with the former first-round pick, according to The Athletic's Diana Russini and Michael Silver and NBC Sports Bay Area's Matt Maiocco. Aiyuk signed a four-year, ...