We recently identified a high prevalence of mutations affecting the catalytic (Cα) subunit of protein kinase A (PKA) in cortisol-secreting adrenocortical adenomas. The two identified mutations ...
Corticotropin-independent Cushing's syndrome is caused by tumors or hyperplasia of the adrenal cortex. The molecular pathogenesis of cortisol-producing adrenal adenomas is not well understood. We ...
Hosted on MSN
Mastering acid–base titration for lab success
Acid–base titration is more than just mixing acids and bases — it’s a precise method to uncover unknown concentrations and chemical constants like pKa. By tracking pH changes as titrant is added, ...
New research has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of ...
Values can be accurately determined in the presence of impurities. The Software seamlessly integrates the collection of electrophoretic separation data, the calculation of compound pKa values, and the ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results