SportsLine's proven model has simulated New York vs. San Diego 10,000 times and released its MLB best bets for Clay Holmes vs. Yu Darvish on Wednesday

The New York Mets (62-46) and the San Diego Padres (59-49) wrap up a 3-game series Wednesday at Petco Park in San Diego. First pitch is scheduled for 4:10 p.m. ET (MLB Network). Let's analyze BetMGM Sportsbook's MLB odds around the Mets vs. Padres odds and make our expert MLB picks and predictions for the best bets.