There’s no bigger game on the NFL slate this week than the one kicking things off on Thursday. The Los Angeles Rams are visiting the Seattle Seahawks in an NFC West showdown at Lumen Field, with the winner taking over sole possession of first place in the division.

The Dallas Cowboys will look to get back on track when they face the Minnesota Vikings in a key NFC matchup on Sunday Night Football. Minnesota is coming off a 31-0 win over the Washington Commanders last Sunday,

The Rams won big in Week 14, and that was important for Matthew Stafford's MVP odds. Stafford is back to being the betting favorite to win MVP after throwing for 281 yards and three touchdowns in a 45-17 blowout of the Cardinals. Stafford is -175 to win MVP. Drake Maye, last week's favorite who had a bye in Week 14, is +200.

NFL Week 16 picks, predictions for every NFL game this week, including Rams-Seahawks, Patriots-Ravens, Chargers-Cowboys, Chiefs-Titans, Packers-Bears.

Ralph Vacchiano is an NFL Reporter for FOX Sports. He spent six years covering the Giants and Jets for SNY TV in New York, and before that, 16 years covering the Giants and the NFL for the New York Daily News. Follow him on Twitter at @RalphVacchiano.