More than 85 years after the discovery of progesterone (P4) by Corner and Allen 1, we have limited understanding of its molecular role in pregnancy maintenance and the initiation of labour.

A single large fibroid may occupy the entire uterine fundus (Panel A, bivalved) and obliterate the endometrial cavity, but many fibroids of varying size can also grow in a single uterus (Panel B).

As the gestation period nears completion, the uterus grows to a length of 12 inches (from 3 inches) and the weight increases to 1,100 g (from 30–40 g). The uterus has 5 liters of fluid, and together ...

The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Uterine leiomyosarcoma is a rare and aggressive cancer that occurs in the uterus. Individuals usually require a hysterectomy. Treatments can also include chemotherapy or radiotherapy. Leiomyosarcoma ...

Adenomyosis is a condition that affects the uterus and is histologically characterized by ectopic endometrial glands and stroma located in the myometrial, which are surrounded by hypertrophic (a ...

The endometrium is the layer of tissue lining the inside of the uterus – the reproductive organ in the pelvis where a baby develops. "The endometrium is a crucial part of the female reproductive ...