Dynamin assembles into a ring around the neck of a forming vesicle and utilizes GTP hydrolysis energy to constrict and sever the membrane. The simulation reveals that the dynamin ring expands (loosens ...

Scientists at the VIB–VUB Center for Structural Biology have uncovered a counterintuitive principle that could reshape how ...

Edward Lyman, associate professor in the departments of physics and astronomy, as well as chemistry and biochemistry, was recently published in the journal Nature Chemical Biology. The article, “When ...

Located at the cellular interface, membrane proteins play critical regulatory roles in the signaling between a cell and its interacting environment, making them popular and ideal drug targets.

Cellular membrane proteins play many important roles throughout the body, including transporting substances in and out of the cell, transmitting signals, speeding up reactions and helping neighboring ...

Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell and its environment ...

Viruses are masters at invading cells thanks to specialized proteins that coat their surfaces. When scientists design ...

The membrane that encases a biological cell is not simply a barrier; it is chock full of proteins involved in all sorts of critical biological functions. To really understand what membrane proteins ...

Membrane proteins are essential for fundamental biological processes, and are important for drug discovery, understanding disease mechanisms, and advancing structural biology. Their intricate roles in ...

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...