As a first step, Chakrabarti and colleagues compared the gene expression profiles of mammary stem cells versus non-stem cells, and found Dll1 to be among the genes most differentially expressed ...

Lab-grown organoids mimic the complexity of organs in vitro and provide insights into biology and disease. Researchers have leveraged organoids developed from mammary glands or tumors to study breast ...

"By understanding a fundamental mechanism of mammary gland development during pregnancy, we have gained a rare insight into how aggressive breast cancer might be treated," said the lead author.

Because the tissue interactions required for mammary gland development cannot be recapitulated fully in cell or organ culture, we have taken a predominately in vivo genetic and pharmacological ...

Our laboratory’s research is based upon the philosophy that it necessary to first define the mechanisms regulating normal mammary gland development in order to understand the alterations in breast ...

To address whether dry bean consumption is associated with a reduction in mammary cancer, scientists at Colorado State University studied the anticancer activity of six market classes of bean ...

Although parity accelerates mammary tumorigenesis, the pattern of tumor development in multiparous MMTV-Neu mice remains stochastic, suggesting that additional events are required for ErbB2/Neu to ...