Figure 1: DNA repair by homologous recombination. An additional activity noted in studies with Brh2 was its ability to promote a template switch. During DNA replication, homologous recombination is ...

Tokyo, Japan – Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a ...

Meiotic recombination is initiated by developmentally programmed double-strand breaks (DSBs), which are subsequently repaired by genetic exchange with allelic sequences. Meiotic recombination pathways ...

A recent study, undertaken by researchers at the Tokyo Metropolitan University and the Tokyo Metropolitan Institute of Medical Science (both Japan), unravels key steps in the process of homologous ...

Impact of Genomic Alterations on Efficacy of Trastuzumab Deruxtecan Against Human Epidermal Growth Factor Receptor-2–Positive Advanced Gastric Cancer This was a prospective, cross-sectional, ...

Precision gene editing is crucial for treating genetic diseases, as it enables targeted correction of specific mutations. A Korean research team has become the first in the world to significantly ...

Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the ...

In men with metastatic castration-resistant prostate cancer who had disease progression while receiving enzalutamide or abiraterone and who had alterations in genes with a role in homologous ...

New findings suggest an explanation for the century-old mystery of how chromosome recombination is regulated during sexual reproduction. In most higher organisms, including humans, every cell carries ...