Researchers from the Mattiroli group have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends ...

Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers—about a millionth of a milliliter. The cell manages this by ...

Inside every cell, inside every nucleus, your continued existence depends on an incredibly complicated dance. Proteins are constantly wrapping and unwrapping DNA, and even minor missteps can lead to ...

A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own version. Cornell researchers have discovered that DNA packaging structures ...

Two new federally funded studies offer detailed views of proteins repairing broken DNA inside tightly packed chromatin, and of the molecular toolkit they assemble at a break, with potential implicatio ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have directly visualized how enzymes find ...

The paper B.W. Bauer et al., “Cohesin mediates DNA loop extrusion by a ‘swing and clamp’ mechanism,” Cell, 184:5448–64, 2021. Approximately 2 meters of DNA is crammed into each of the human body’s ...

Researchers have found that the way DNA is packaged in cells can directly impact how fast DNA itself is copied during cell division. They discovered that DNA packaging sends signals through an unusual ...