High-quality MRI of brainstem tumors is essential in clinical management to localize the lesion and to differentiate focal from diffuse tumor involvement. A focal tumor is typically well marginated, ...

Diffuse intrinsic pontine gliomas (DIPGs), with a median survival of 9 months, represent the biggest therapeutic challenge in pediatric neuro-oncology. Despite many clinical trials, no major ...

New diagnostic criteria have been introduced for neuromyelitis optica (NMO), which is now to be known as neuromyelitis optica spectrum disorder (NMOSD). The new criteria were developed by an ...

A 43 year-old man had a twenty year history of MS, presenting initially with optic neuritis. Over the past ten years, he developed progressive weakness, numbness and ataxia in the lower extremities.

A 25 year-old woman with multiple sclerosis presented with worsening spasticity and ataxia. Multiple Sclerosis (MS): T1-weighted with gadolinium axial MRIs. Note the numerous lesions that enhance with ...