The study details the connection between SCARB2 deficiency and gastrointestinal dysfunction, revealing that the loss of SCARB2 leads to alterations in bile acid metabolism and dysbiosis in the gut ...
Fewer than half of patients with FIC1 deficiency have their native liver at age 18. The number of PPTMs did not reliably predict the phenotype. However, sBA concentrations at baseline and after SBD ...
An international research team has uncovered compelling evidence that gut-microbe-derived molecules may play an important ...
The VDR is a member of the steroid/hormone nuclear receptor superfamily that includes 48 ligand-activated transcription factors. [3] These factors bind to conserved elements in the promoters of genes ...
Please provide your email address to receive an email when new articles are posted on . Treatment with maralixibat led to greater reductions in least-squares mean change from baseline in morning ...