The ability of plants to grow faster and stronger is traced to autophagy, along with key enzymes and proteins such as AFR7, ...

Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...

Aging and cancer are deeply intertwined: advancing age is the single largest risk factor for most malignancies, and many of the molecular processes that ...

In a recent study published in the journal Neuron, researchers at the University of Cambridge and Newcastle University, UK, examined the relationship between autophagy, aging, and neurodegeneration.

Researchers in Spain have found that chaperone-mediated autophagy, a selective protein cleanup process, is markedly reduced in the motor neurons of ALS patients. The deficiency may contribute to toxic ...

From PCR and CRISPR to autophagy and targeted cancer therapies, scientists share the discoveries that shaped their work and ...

Findings underpin the scientific rationale for Anavex’s targeted autophagy approach with orally administered blarcamesine Convergence of impaired autophagy and synaptic dysfunction across ...