How many ways can a troponin assay come up with a false positive or a false negative? In this episode of AP Cardiology, Andrew Perry, MD, tallies it up with Robert Christenson, PhD, of the University ...
Interference in laboratory assays is a concern since it can positively or negatively influence test results, which can affect patient care. Interferents could be endogenous or exogenous compounds.
You run the assay. The values come back off. Not catastrophically wrong, just inconsistent enough to make you doubt everything. You've checked the protocol twice. The kit hasn't expired. But the CV is ...
Luminescence and fluorescence-based assay methods prevail in modern HTS. Although invaluable as technologies, the problem of compound-related assay interferences such as quenching, auto-fluorescence, ...
Immunoassays used for human in vitro diagnostics (IVD) often use animal-sourced antibodies to recognize specific disease markers. A small percentage of individuals, however, may have antibodies in ...
Avoiding immunoassay interference requires blockers to be included in every immunoassay. Historically, animal-based interference blockers have been used to improve assay accuracy; however, they are ...
The core principle of BETMAT’s Kinetic Chromogenic LAL Assay is based on the specific enzymatic cascade triggered by the interaction between Limulus Amebocyte Lysate (LAL) and bacterial ...
Increasingly accessible to academic researchers, high-throughput screening (HTS) is one of the best ways to discover starting points for new chemical probes and first-in-class drug candidates. However ...
Luminescence screening assays have become a central component of modern drug discovery workflows, particularly in high-throughput screening (HTS) environments. These assays enable rapid, sensitive ...
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