The ß-ARs play an important role in CV health and disease and are mainstay targets of ß blockers in the treatment of hypertension, congestive HF, and coronary disease. Both genetic association and ...
Recent clinical studies have suggested that phenylacetylglutamine (PAGln), a novel gut microbial metabolite, can mechanistically modulate patients' risk of developing cardiovascular disease (CVD) and ...
Taste, pain, or response to stress -- nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers have uncovered the ...
As a neuromodulator, norepinephrine is a powerful force in the brain. We all know it orchestrates rapid changes in behavior such as the fight-or-flight response. Fewer people know that astrocytes ...
Background Sympathetic signalling plays a critical role in the initiation and progression of various malignancies. However, ...
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