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Cubs vs White Sox Picks, Odds and Prediction

Chicago Cubs at Chicago White Sox odds, picks and predictions

The Chicago Cubs (60-42) visit the South Side of Chicago to face the Chicago White Sox (37-66) Friday in the first game of a 3-game interleague series. First pitch from Rate Field is at 7:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Cubs vs. White Sox odds and make our expert MLB picks and predictions for the best bets.

CBS Sports · 45m

Cubs vs. White Sox prediction, odds, props, best bets: Free 2025 MLB picks for Friday, Illinois sports betting

SportsLine's proven model has simulated the Chicago White Sox vs. Chicago Cubs 10,000 times and released its MLB best bets for Illinois sportsbooks

NBC Sports on MSN · 1h

Cubs at White Sox Prediction: Odds, expert picks, starting pitchers, betting trends, and stats for July 25

It’s Friday, July 25 and the Cubs (60-42) are in Chicago to take on the White Sox (37-66). Shota Imanaga is slated to take the mound for Chicago against Adrian Houser for Chicago. The Cubs are 1-3 in the past four games and coming off a series loss to the Royals where they dropped two of three.

3 MLB trade deadline moves for Chicago

Newsweek on MSN · 2h

MLB Insider Reveals Cubs' Expected Trade Deadline Approach

The Chicago Cubs could be one of the more intriguing teams to follow at the trade deadline. What could their approach be at the deadline?

CBS Sports · 23h

Playing GM for the Cubs: Three MLB trade deadline moves for Chicago after losing NL Central lead

The Chicago Cubs haven't been to the playoffs in a full season since 2018 and that was just one game, as they lost the Wild Card back when it was a one-and-done. They're coming off back-to-back 83-win seasons.

Sports Illustrated on MSN · 20h

MLB Mock Trade: Minnesota Twins Deal Joe Ryan To Chicago Cubs

The Twins also receive the Cubs' top pitching prospect, Jaxon Wiggins, who has quickly ascended through the minors. After being drafted in the second round of the 2022 MLB Draft, he underwent Tommy John surgery in 2023. Now, in 2025, he’s pitching to a 2.25 ERA across 36 innings with 48 strikeouts in Double-A.

FOX 32 Chicago on MSN7h

Crosstown Classic: Cubs and White Sox bring differing energies to Chicago rivalry this weekend

Earlier this year, the Cubs were red-hot and the Sox were anything but in the Crosstown Classic at Wrigley. The two renew ...

56mon MSN

Cubs Should Go After Hated Rival's Former Star Pitcher After Shocking DFA

The Chicago Cubs have long been expected to be one of baseball's most aggressive teams at next week's trade deadline.

19h

Cubs Could Add Pete Crow-Armstrong Insurance, Per Chicago Insider

Cubs Could Add Pete Crow-Armstrong Insurance, Per Chicago Insider originally appeared on Athlon Sports. If past indications ...

2hon MSN

Latest Report Indicates Cubs Targeting AL East for Reliever Help

Recent reports have indicated that the Chicago Cubs are targeting two pitchers from the AL East to help improve their bullpen ...

10hon MSN

Chicago Cubs fans excited about reports MLB All-Star Game coming to Wrigley Field in 2027

Chicago Cubs fans shared their excitement with ABC7 about multiple reports saying the MLB All-Star Game will come to Wrigley ...

3don MSN

Kansas City Royals and Chicago Cubs play in game 2 of series

Kansas City is 25-26 in road games and 49-52 overall. Royals pitchers have a collective 3.50 ERA, which ranks second in MLB ...

13hon MSN

Former Cubs Pitcher Jesse Chavez Announces Retirement from Professional Baseball

It doesn't look like veteran starting pitcher Jesse Chavez will be resigning with the Atlanta Braves anytime soon.

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