The London Stadium will hold host to a game between two sides in the bottom four on Saturday afternoon, with hosts West Ham looking to climb out of the relegation zone while Burnley will be wary of

West Ham have the chance to climb out of the relegation zone as they face a Burnley side one place above them in 17th in the table on Saturday (15:00 GMT). BBC Sport examines some of the key themes before the match.

West Ham host Burnley in the Premier League on Saturday as it heats up early on in the relegation battles. West Ham vs Burnley best bets Bet on West Ham to win at 10/11 on Sky Bet Back Over 4.5

Preview the matchup between West Ham United and Burnley FC with predictions, odds, over/under, betting lines and more.

West Ham boss Nuno Espirito Santo has been speaking to the media before Saturday's Premier League game against Burnley at London Stadium (kick-off 15:00 GMT). Here are the key lines from his news conference:

Burnley manager Scott Parker has opened up about losing some key players to the Africa Cup of Nations in January, including Bafana Bafana striker Lyle Foster. The Cup of Nations gets underway in Morocco next month and teams in Europe are set lose their African stars for month.

Burnley striker Ashley Barnes said he had expected to net his 100th senior goal earlier in his career but the 31-year-old was delighted the special moment came in Thursday's 1-0 victory over Premier League champions Liverpool.

Arsenal are seven points clear of the field in the Premier League title race (for the time being) after beating Burnley 2-0 at Turf Moor, thanks to two more headed goals from Viktor Gyokeres and Declan Rice.

Arsenal are already without Kai Havertz, Gabriel Jesus, Noni Madueke, Martin Odegaard, and Gabriel Martinelli all due to injury issues.

Scott Parker says he can see his Burnley squad growing collectively, following their excellent recent form.They have won two of their last three games in the Premier League, against Leeds and Wolves.